SYMPOSIUM 1From systems to organelles – understanding pancreatic beta cell function and dysfunction

Miriam Cnop (Belgium) – Using functional genomics to identify mechanisms of beta cell dysfunction in diabetes
Lício Velloso (Chair – Brazil) – Common mechanisms and cross talk between brain and pancreatic beta cells in diabetes
Michael Sammeth (Brazil) – A systems biology approach to integrate complex data in pancreatic beta cell research
Doris Stoffers  (USA) – Key transcription factors that regulate beta cell function and survival
Flemming Pociot (Denmark)
– Long non-coding RNAs regulate pancreatic beta cell function and dysfunction in diabetes

Sponsored by CEPID – Obesity and Comorbidities Research Center – UNICAMP/USP/UNESP/FAPESP 

SYMPOSIUM 2The Exercise Pressor Reflex as a Mediator of Sympathetic Overactivity in Cardiovascular Disease

Donal S. O’leary (USA) – Neural control of cardiovascular activity during dynamic exercise in heart failure
Scott A. Smith (USA) Exercise Pressor Reflex Dysfunction in Hypertension
Carlos Eduardo Negrão (Brazil) – Effect of Exercise Training on Muscle Mechanoreflex and Metaboreflex Control in Human with Chronic Heart Failure
Hanjun Wang (Chair – USA) – Mollecular and Cellular Determinants of the Exercise Pressor Reflex in Heart Failure
Denise Moreira Lima Lobo (Brazil) – Neurovascular Responses During Chemoreceptors Stimulation in Systolic Heart Failure Patients with Sleep-Disordered Breathing

SYMPOSIUM 3Intracellular Cl- (Cl-in) sensing in cell signaling and ion transport

Shmuel Muallem (Chair – USA) Cl-in sensing in the regulation of Na+/HCO3-transporters
Melanie Cobb (USA) – WNK kinases as Cl-in sensors
Maurício Ostrosky-Frid (Mexico) – Chloride modulation of WNK4 effect on NCC and the relevance for potassium metabolism
Laura Cancedda (Italy) – Accumulated Cl- reverses GAMAAR signaling in Down syndrome

SYMPOSIUM 4 A search for new epithelial magnesium transporters and channels in health and disease

Alexey G. Ryazanov (USA) – Epithelial magnesium transport by TRPM6
Yosuke Funato (Japan) – CNNM magnesium transporters in health and disease
Jeroen de Baaij (Chair – Netherlands) SLC41 magnesium transporters in epithelia
Frederica Wolf (Italy) – Magnesium and its transporters in cancer 

SYMPOSIUM 5Oxytocin oscillations throughout the life span

Kewir Nyuyki-Dufe (Canada) – Hypothalamic oxytocin pulses triggered by mating in males and females: Consequences for anxiety and stress responses
Ioana Carcea (USA) – Large-scale behavioral and physiological analysis for the role of oxytocin in maternal interactions
Aldo Bolten Lucion (Brazil) – Oxytocin: mother-infant attachment and separation
Inga D Neumann (Chair – Germany) – When things go wrong: Anxiolytic, fear-reducing and anti-stress effects of oxytoci

SYMPOSIUM 6The Physiology of Polycystic Kidney Disease: New Molecular Pathways and Therapeutic Targets

Michael Caplan (Chair – USA) –The polycystin proteins as oxygen sensors and regulators of cellular energy metabolism
Alessandra Boletta (Italy) – Metabolic alterations in Polycystic Kidney Disease
Dorien J. Peters (Netherlands) – Polycystic kidney disease: How tissue contexts affect cystogenesis
Luiz F. Onuchic (Brazil) – Mechanisms of cardiac dysfunction associated with polycystic kidney disease

SYMPOSIUM 7New discoveries in tissue cross-talk, metabolic control and disease pathogenesis

Bente Klarlund Pedersen (Denmark) – Muscles, exercise and obesity: skeletal muscle as a secretory organ
Matthew Watt (Chair – Australia) – Liver secreted factors impact metabolic homeostasis in health and disease
Kasey Vickers (USA) – Cross-kingdom Gene Regulation by Lipoproteins
Mark Tarnopolsky (Canada) – Characterization of novel exersomes: from systemic metabolic effects to treating neuromuscular disorders

SYMPOSIUM 8Dyadic and T-Tubule Remodelling in Cardiac Health and Disease

Andrew Trafford (Chair – UK) – AmpII as a key player in ventricular T-tubule biogenesis and target for heart failure therapies
Alicia Mattiazzi (Argentina) – How does CAMKII modulate dyadic function in health and disease
Katharine Dibb (UK)  – Atrial T-tubules, their functional significance and restoration on recovery from heart failure
Ting Ting Hong (USA) – Ion Channel Trafficking to T-tubules 

SYMPOSIUM 9Oscillations in neuronal ensembles of frontal cortex and the basal ganglia circuits implications for neurologic and psychiatric disease

Per Petersson (Chair – Sweden) – Information processing in cortico-basal ganglia-thalamic network in health and disease.
Romulo Fuentes (Chile) – Neuromodulatory approaches targeting network oscillations in cortico-basal ganglia circuits
Ivani Brys (Brazil) – Role of high-frequency oscillations in psychiatric conditions
Claudio da Cunha (Brazil) – The role of the basal ganglia in action-selection

SYMPOSIUM 10New insights in the molecular physiology of the renal distal nephron
Jenny van der Wijst (Chair – Netherlands) – Regulation of magnesium transport in the distal part of the nephron.
Gerrit Daubner (UK) The WNK-SPAK/OSR1 pathway in general
Eisei Sohara (Japan) – WNK kinase signalling to cátion chloride transporters
Sung-Sen Yang (Taiwan) – Molecular regulation of sodium-chloride cotransporter NCC

SYMPOSIUM 11 – Heart Failure and Atrial Fibrillation: Imbalance of Calcium Homeostasis

William Louch (Chair – Norway) –New Insight into Control of Dyadic Structure in Cardiomyocytes
Cecilia Hidalgo (Chile) – Redox Modifications of Ryanodine Receptors
Bjorn Knollmann (USA) – Inhibition of pathological calcium release for preventing atrial fibrillation in mice and humans.
Morten Thomsen (Denmark) – KChiP2 and the failing heart.
Shi-Qiang Wang (China) – Beta-adrenergic regulation of intracellular calcium dynamics in health and CPVT cardiomyocytes 

SYMPOSIUM 12Physiological and pathophysiological changes in the transcriptome: New targets for understanding autonomic regulation

David Murphy (UK) – From transcriptome to physiology: novel insights into hypothalamic function
Alastair V. Ferguson (Canada) – Genomic analysis of the subfornical organ: information overload or the key to understanding integrated physiological functions?
Sabine Gouraud (Japan) – Deciphering the transcriptome of hypertensive nucleus tractus solitarii to unmask blood pressure regulation mechanisms.
Alex Paterson (UK) – Hypertension: Environment-Genome Interface
Andre Souza Mecawi (Chair – Brazil) – Reducing sodium intake: impacts on neurohypophysial system transcriptome and physiology

SYMPOSIUM 13 – Seasonal adjustments in Physiology: anticipatory or reflexive

Charles Loren Buck (USA) – Circannual and circadian rhythms of an arctic squirrel
Fritz Geiser (Australia) – Seasonal changes in the expression of torpor in birds and mammals
Dehua Wang (China) – Seasonal changes in thermogenesis and energy metabolism in small mammals in China.
Danielle Levesque (USA) – Seasonal cycles of body temperature and hibernation in free-ranging tenrecs
Kenia Cardoso Bicego (Chair – Brazil) – Seasonal physiology in a facultative endothermic lizar

SYMPOSIUM 14 – Cellular and molecular aspects of synaptic transmission

Yuko Sekino (Chair – Japan) – Drebrin dynamics in synaptogenesis.
Christian Gonzalez-Billault (Chile) – Pre- and postsynaptic functions of the microtubule-associated proteins
Tomoaki Shirao (Japan) – Novel actin-dependent mechanism of synaptic plasticity
Shernaz Bamji (Canada) – Regulation of synaptic plasticity, learning and addiction by cadherin adhesion complexes

SYMPOSIUM 15Management and mismanagement of a physiological pH buffer: New concepts about CO2/HCO3 fluxes across biological membranes.

Walter Boron (Chair – USA)
Fraser J. Moss (USA)  Extracellular sensing of molecular CO2 and HCO3.
Ernesto Alejandro Aiello (Argentina)
– Pathophysiological role of the sodium/bicarbonate cotransporter (NBC) in the heart.
Raif Musa-Aziz (Brazil) – Pathways for COand/or NH3 transport across cell membranes.
Mark D. Parker (USA) – Bicarbonate transporters and eye pathophysiology.

SYMPOSIUM 16 – Autonomic rhythms in health and disease

Susan Deuchars (Chair – UK) – Changing levels of rhythmic sympathetic nerve activity
Song Yao (Australia) – Blood-brain barrier and autonomic rhythms
Ruth Stornetta (USA) -Pre-sympathetic C1 neurones: a nodal point for stress?
Alex Gourine (UK) – Glial control of autonomic circuits 

SYMPOSIUM 17 – New insights into the biology of high-intensity exercise training

Nir Eynon (Chair – Australia) – The Gene SMART study provides insights into the genetic influence on adaptations to high-intensity training
Guilherme G. Artioli (Brazil) – Can high-intensity exercise training increase muscle carnosine content?
David Bishop (Australia) – High-intensity exercise training and mitochondrial biogenesis
Maureen MacDonald (Canada) – High-intensity exercise and cardiovascular function
Bareket Falk (Canada) – High-intensity exercise and bone physiology in adults and children.

SYMPOSIUM 18 – Cardiovascular Consequences of Pollution

Fabien Brette (France) – Effects of Oil Spill Toxicity on Cardiac Myocytes from Oceanic Predators
Holly Shiels (Chair – UK) – Poly Aromatic Hydrocarbons and Mammalian Arrhythmogenesis
John Incardona (USA) – Developing heart form follows function: Morphological consequences of PAH cardiotoxicity
Elin Sorhus (Norway) – RNA-Seq reveals novel impacts of PAHs on excitation-transcription coupling in cardiomyocytes
Mark Miller (UK) – The impact of air pollution on human hearts

SYMPOSIUM 19 – Promoting Ethical Practices in Physiological Research

Penny Moody-Corbett (Canada) – Ethics in the Research Lifecycle
Ashima Anand (Chair – India) – International perspectives on research integrity: update from The World Conferences of Research Integrity
Sonia Vasconcelos (Brazil) – Education and governance in research integrity: examples from the Americas
Bill Yates  (USA) – Publication standards, adhering to research integrity

SYMPOSIUM 20  – Obesity, sleep disorder and arterial hypertension, is that your choice? Novel mechanisms for cardiovascular control and programming of obesity

Virend K. Somers (USA) – Sleep Apnea and Sleep Deprivation: Implications of inadequate sleep for obesity, hypertension and cardiometabolic risk.
Egberto C. Moura (Brazil) – Lactation is an important period to decrease the risk of obesity and cardiovascular risk
Jussara M. do Carmo (USA) – Regulation of metabolic and cardiovascular function by the brain leptin-melanocortin pathway: What is new?
Alan Kim Johnson (USA)  The effects of early life experiences on the etiology of hypertension.
Mirian Bassi (Chair – Brazil) – Obesity, leptin and breathing control

SYMPOSIUM 21 – What experimental models of human diseases have taught us?

Patricia Rieken Macedo Rocco (Brazil) – Acute respiratory distress syndrome: what experimental models have taught us?
Claudia dos Santos (Chair – Canada) – Experimental sepsis: the role of genomics, proteomics, bioinformatics and translational biology.
Bela Suki (USA) – Lung structure-function relations in experimental emphysema.
Walter Zin (Brazil) – Understanding acute and chronic air pollution and their impact on lung function

SYMPOSIUM 22Physiologists Reach Out to School Students to Entice Future Physiologists!

Barbara E. Goodman (Chair – USA) – Outreach Programs to School Children through the American Physiological Society
Pâmela Billig Mello-Carpes (Brazil) – Brazilian outreach actions to promote physiology learning and teaching in secondary and high schools
Frankie MacMillan (UK) – University of Bristol Physiology Outreach Strategy; to whom are we reaching out?
Manish Bajpai (India) – Prarambh/Initiation of Basic Life Science Skills
Rudolf  Schubert (Germany) – News in physiology presented by young physiologists at secondary schools in Germany

SYMPOSIUM 23Integrated Neural-Glial-Vasculature Control of Breathing

Daniel K. Mulkey (Chair – USA) – Purinergic signaling provides specialized control of vascular tone in the retrotrapezoid nucleus to support the CO2/H+-dependent drive to breathe
Gregory D. Funk (Canada)The role of P2Y1 receptor signaling in central respiratory control.
Hiroshi Onimaru (Japan) – Relationship between the distribution of the paired-like homeobox gene (Phox2b) expressing cells and blood vessels in the parafacial region of the ventral medulla of neonatal rats.
Fernando Peña-Ortega (Mexico) – Glial modulation of pre-Bötzinger complex plasticity.
Luciane H. Gargaglioni (Brazil) – Breathing control in rats after in utero and post-natal manipulations.

SYMPOSIUM 24 – New insights into the pathogenesis of Parkinson’s disease

Jiawei Zhou (Chair – China) – Differential signaling by Hsp22 and Bag3 in midbrain dopaminergic neurons determines susceptibility to neurotoxins via autophagy pathway.
Yizheng Wang (China) – Contribution of Dicer to neuronal survival in the mouse PD models.
Elaine Del-Bel (Brazil) – New avenues for the treatment of L-DOPA-induced dyskinesias in Parkinson’s disease: targeting nitric oxide, glutamate and inflammation
Rodrigo Pacheco (Brazi) – Dopamine-driven inflammation in the gut and the brain


SYMPOSIUM 25  – Teaching Comparative Physiology: Multiple Approaches Promoting Learning

Malcolm S. Gordon (Chair – USA) – Hands-on experiential approaches in teaching comparative physiology
Stacy Farina (USA) – Cutting-edge teaching at the edge of the ocean: the role of field courses in reforming physiology education
Miriam Struchiner – (Brazil) Research and Development of Information and Communication Technology
Marcia Trapp (Brazil) – Learning Objects in Teaching Physiology: Alternative Methods to the Use of Animals in Practical Classes on Animal Physiology
Cuijuan Niu (China) – Animal physiological ecology – research and education of animal comparative physiologyfrom a environment adaptation perspective

SYMPOSIUM 26 – Piezo channel mechanisms in health and disease

Boris Martinac (Australia) – Mechano-sensing channel mechanisms
David Beech (Chair – UK) – Piezo1 in vascular biology
Bailong Xiao (China) – Piezo1 channel structure
Philip Gottlieb (USA) – Piezo channel regulatory domains
Pia Ostergaard (UK) – Piezo1 in non-immune hydrops fetalis

SYMPOSIUM 27 – Polymodal Properties of Carotid Body Chemoreceptors Beyond Hypoxia: Relation to Health and Disease

Harold D. Schultz (Chair – USA) – Transcriptional regulation of carotid body function by blood flow
Jacqueline K. Limberg (USA) – The carotid body chemoreceptors and glucose regulation in humans
Silvia Vilares Conde (Portugal) – Carotid body: a metabolic sensor implicated in insulin resistance
Colin A. Nurse (Canada) – The role of glial-like type II cells as paracrine modulators of carotid body chemoreception
Nanduri R. Prabhakar (USA) – Epigenetic regulation of carotid body O2 sensing

SYMPOSIUM 28 TRP channels: structure, function and regulation

Ligia Araujo Naves (Chair – Brazil)
Ramon Latorre (Chile) – Allosterism in thermoTRP channels.
Sharona E. Gordon (USA) – Mechanism of multimodal gating in TRPV1 ion channels
Laszlo Csanady (Hungary) – Converting three input signals into a single readout: structure and function of the TRPM2 channel
Tamara Rosenbaum (Mexico) – The link between pain, itch, fatty acids and TRPV1.

SYMPOSIUM 29 – Cardiorespiratory interactions – from animals to humans

Erin OCallaghan (UK) – Respiratory modulation of cardiac sympathetic nerves in rat
Alona Ben-Tal (new Zealand) – Mathematical modeling of cardiorespiratory system
Rohit Ramchandra (New Zealand) – Respiration and heart failure in sheep
Maja Elstad (Chair – Norway) – Hemodynamic interactions between respiration and circulation in humans

SYMPOSIUM 30 – The Sigh: A biological rhythm in the interface between physiology and psychology

Jan Marino Ramirez (USA) – Neuronal mechanisms of rhythm generation of the sigh
Muriel Thoby-Brisson (France) – Development of the neuronal network underlying sigh
Peter Burke (Australia) – Sigh and the coupling to the noradrenergic arousal system
Elke Vlemincx (Chair – Belgium) –The role of sighs in controlling emotional states in humans

SYMPOSIUM 31 – Dynamic methods for improving undergraduate physiology education

Pâmela Billig Mello-Carpes (Chair – Brazil)
Barbekka Hurtt (USA) – Multi-modality learning: Implementation of 3D simulation alongside traditional lab education methods in anatomy and physiology
Fernanda Klein Marcondes (Brazil) –Combined use of educational games and quizzes in physiology teaching
Colleen Thomas (Australia) – Animating textbook images: Tackling roadblock physiological concepts in the online subject delivery era
Kathleen Marie Bartlow (USA) – Using Brain Awareness Week as a teaching tool
Maria José Alves da Rocha (Brazil) – Using interactive systems and virtual platforms to engage students in learning and understanding physiology

SYMPOSIUM 32 – New roles of Aldosterone and Mineralocorticoid receptors in cardiovascular disease: Translational and Sex-specific effects

Frederic Jaisser (France) – Repositioning Mineralocorticoid receptor antagonists: pathological basis and therapeutic implications
Iris Jaffe (USA) – The Role of Smooth Muscle Cell Mineralocorticoid Receptors in Cardiovascular Aging
Rita Tostes (Brazil) – Role of the NLRP3/Inflammasome on Aldosterone-induced vascular damage
Eric J. Belin de Chantemele (Chair – USA) – Leptin-mediated aldosterone secretion: a major contributor to cardiovascular disease in obese female mice
Ana Paula Davel (USA) – Mechanisms of endothelial dysfunction due to cardiometabolic risk factors: sex differences in the role of endothelial mineralocorticoid receptor

SYMPOSIUM 33 – Shared and unique aspects of the gating mechanisms of ligand- and voltage-gated ion channels

Yoshihiro Kubo (Chair – Japan) – Activation mechanisms and binding sites of ivermectin in G-protein-gated inwardly rectifying potassium channels
Derek Bowie – (Canada) – Structural and functional biology of the glutamatergic synapse
Cecilia Bouzat (Argentina) – Molecular bases of function and drug modulation of α7 nicotinic receptors: Implications for drug discovery
Frank Bosmans (USA) – Architecture of the sodium channel signaling complex
Marc Gielen (France) – Structural basis of inhibitory Cys-loop receptor desensitization

SYMPOSIUM 34 – Calcium handling and mishandling: Role in Cardiac Rhythm and Dysrythmia

Yael Yaniv (Israel) – The coupled clock pacemaker system
Ana Mara Gomez (France) – Regulation of RyR2 by L tipe Calcium channel in the sino-atrial pacemarker activity
Francisco Alvarado (USA) – Ryanodine receptors: Function and regulation
Martin Vila Petroff (Chair – Argentina) – Role of CaMKII in RyR2 regulation and Calcium triggered arrhythias
Filip L.A. Van Petegem (Canada) – High resolution insights into calmodulin regulation and misregulation of cardiac ion channels

– Role of Redox Stress and Epigenetics in Ageing

Giovanni E. Mann (Chair – UK) – Gestational diabetes induced redox and epigenetic stress: consequences for cardiovascular dysfunction in offspring
Jose Viña (Spain) – Molecular mechanisms underlying health benefits of exercise in human ageing
Renu A. Kowluru (USA) – Epigenetic regulation of diabetic retinopathy in aging
Holly van Remmen (USA) – Dysregulation of mitochondrial redox signaling and consequences for skeletal muscle aging

SYMPOSIUM 36New insights into physiological and clinical adaptations to exercise and their heterogeneity

Bethan Phillips (UK)
– The heterogeneity and efficacy of pre-operative high-intensity interval training in cancer patients
Philip J Atherton (Chair – UK) – The impact of age on metabolic and molecular governance of exercise adaptation
Heikki Kainulainen (Finland) – Alternative exercise modes for the low responder to exercise
Patricia Brum (Brazil) – Exercise training for counteracting skeletal myopathy in chronic diseases: relevance to heart failure and cancer
Vitor Lira (USA) – Muscle autophagy and the exercise training-mediated benefits in obesity and diabetes.

SYMPOSIUM 37 – New insights into prolactin regulation and functions: a key hormone integrating reproduction and metabolism

Damasia Becu-Villalobos (Argentina) – Intertwined dialogue of prolactin, growth hormone and dopamine receptors in food intake, glucose balance and adiposity regulation
Jose Donato Jr. (Brazil) – Anti-diabetic potential of manipulating prolactin signaling
Raphael E. Szawka (Brazil) – New insights into prolactin interaction with gonadal axis and its role in fertility
Patrice Mollard (France) – In vivo monitoring of the activity and regulation of the prolactin network
David R. Grattan (Chair – New Zealand) – Prolactin action in the medial preoptic region is essential for post partum maternal behaviour 

SYMPOSIUM 38 – From synaptic and network plasticity to behavior

Juan Lerma (Spain) – Behavioral impact of altering synaptic gain
Ying-Shing Chan (Chair – China) -Developmental plasticity of brain circuits for navigational behavior
Jinshun Qi (China) – A novel unimolecular GLP-1/GIP/GCG triagonist improves the cognitive behavior and hippocampal pathology in 3xTg-AD mice.

Sponsored by Chinese Association Phisiological Science (CAPS)

SYMPOSIUM 39 Cilia go by the flow

Helle Praetorius (Chair – Denmark) – The primary cilium as sensor of fluid flow
Jose Badano (Uruguay) – Ciliary Physiology: understanding the cellular and genetic basis of human ciliopathies
Iain Drummond (USA) – Cilia function in Zebrafish
Surya Nauli (USA)  Functional mechanisms of the primary cilium.

SYMPOSIUM 40 – Vasomotion – the rhythm of blood vessels

Aneta Stefanovska (UK) – Flowmotion in the skin – data collection and analysis
Vladimir Matchkov (Chair – Denmark) – Chloride channels are important for vasomotion
Antonio Colantuoni (Italy) Mechanisms of capillary blood flow regulation: the role of vasomotion

SYMPOSIUM 41 –  Synapse function in the immune system

 Claudio G. Giraudo (USA) – New mutations in Stxbp2 affect granule fusion of the immunological synapse
Hsin-Fang Chang (Germany) – Endocytosis of cytotoxic granules at the immunological synapse”
Jennifer L. Stow (Australia) – Cytokine secretion: SNAREs, Rabs and membrane trafficking”
Yenan T. Bryceson (Chair – Sweden) – Immune deficiencies in humans 

SYMPOSIUM 42Newly recognized G protein-coupled receptors (GPCRs) as novel regulators of physiology

Stefan Offermanns (Germany) – Molecules that are generated during metabolism–including fatty acids, saccharides, lactate and ketone bodies.
Debbie L. Hay (New Zealand) – Novel neuropeptide receptors in pain physiology
Jennifer Pluznick (USA) – Novel Roles for Orphan GPCRs in renal physiology
James Eberwine (USA) – Identification of endogenously expressed GPCRs using single-cell transcriptomics 

SYMPOSIUM 43 – Mathematical Models in Health and Disease

Denis Noble (UK)The importance of using mathematical models in physiological research
Elena Lascano (Chair – Argentina) – Mathematical models of the cardiovascular system
Juan Ignacio Felice (Argentina) – Mathematical models of cardiomyocytes
Kelly C. Iarosz (Brazil) – Cellular automata in biophysics

SYMPOSIUM 44 – Mechanisms of mitochondria function and dysfunction

Satoshi Matsuoka (Japan) – Na/Ca exchange and Mitochondria function. The use of Mathematical models.
Donald Bers (USA) – The physiological role of mitochondrial calcium
Heping Cheng (Chair – China) – Mitoflash signaling in health and disease.
Yuriana Oropeza (Mexico) – Mitochondrial dysfunction in heart failure
Alejandro Ciocci Pardo (Argentina) – Post-ischemic mitochondrial state: role of electrogenic Na+/HCO3- cotransporter and carbonic anhydrase

Evolution Evolves: Physiology returns to Centre Stage 

David Paterson (Chair – UK)
Michael Joyner (USA) – Chasing Mendel. Thinking about genotype versus phenotype
Yoav Soen (Israel) – Adaptation by Natural Improvisation
Abigail Fowden (UK) – Inherited Maternal effects
Yonghua Sun (China) – Maternal effects on embryonic development by using fish knockout models

SYMPOSIUM 46 – The Two-way Physiology Street: Mutual benefits of volunteering expertise

Penelope A. Hansen (Canada) – Not a physician? What is a physiologist doing on a medical team?
Tony Macknight (Chair – New Zealand) – Education Workshops. Who really benefits?
Anisha Taylor (UK) – Lab_13 Ghana: Creative learning in resource constrained environments
Olusoga A. Sofola (Nigeria)An Informal Research Assistance Arrangement to Enhance Capacity Building of Young Researchers in Physiology in Nigeria

SYMPOSIUM 47 – Neuroendocrine alterations in the hypothalamus by excess nutrients and endocrine disrupting chemicals causing metabolic disorders

Denise D. Belsham (Chair – Canada) – Detrimental effects of high fat or high sugar on neuropeptide synthesis and circadian rhythms in cell models from the hypothalamus.
Deborah Kurrasch (Canada) – Endocrine-disrupting chemicals and their effects on hypothalamic development.
Sarah A. Stanley (USA) – Remote control of neurons to analyze glucose metabolism.
Deborah J. Klegg (USA) – Estrogens and their receptors regulate the hypothalamic response to nutrients

SYMPOSIUM 48 – Circadian rhythms and gastrintestinal physiology

Karl-Heinz Herzig (Chair – Finland)
Patricia Brubaker (Canada) – Circadian secretion of the intestinal hormones
Guillaume de Lartigue (USA) – Clocks and vagal signaling
Charna Dibner (Switzerland) – Molecular mechanisms of clocks and their effects on insulin release.

SYMPOSIUM 49 – Wild clocks: Temporal organization of physiology and behavior in natural settings

Barbara Helm (UK) –Temporal multitasking: programs and plasticity of migratory birds on different time scales.
Horacio De La Iglesia (USA)Sleep Under “Natural” Conditions
Cory T. Willians (USA) – Entraining to the polar day: circadian rhythms in arctic vertebrates
Gisele A. Oda (Chair – Brazil) –Daily and annual photic synchronization in a subterranean rodent
Carlos Candia-Gallardo – Adaptative responses in changing environments: annual cycles of butterflies during atypical rainfall regimes

SYMPOSIUM 50Scope for Survival: Animals in Extreme Environments

Marina Giacomin (Canada)Management of oxygen stores while diving at depths
William K. Milsom (Chair – Canada) – Hypoxia adaptations for life at altitude
Tobias Wang (Denamark) – Balancing water and energy budgets in the desert
Julia Nowack (Austria) – Can heterothermy facilitate the colonization of new habitats?
Paul Ponganis (USA) – Management of oxygen stores while diving at depths

SYMPOSIUM 51 – Oxygen variation through time

Wilfried Klein (Chair – Brazil)
Jason E. Podrabsky (USA) – Developmental adaptations to hypoxia and anoxia in the annual killifish Austrofundulus limnaeus
Gina Galli (UK) – The impact of developmental phenotypic plasticity and hypoxic incubation on Juvenile reptile cardiovascular function.
Markus Lambertz (Germany) – Amniote lungs: A pulmonary perspective on terrestrial vertebrate evolution.

SYMPOSIUM 52 – The renin-angiotensin system: going beyond the classical paradigms

Robson A.S. Santos (Chair – Brazil) – Identification and characterization of a novel family of angiotensin peptides in human plasma: Alatensins
Michael Bader (Germany) – Mas-related receptors and the Renin Angiotensin System
Ulrike Muscha Steckelings (Denmark) – The Angiotensin AT2 Receptor: Frrom enigma to therapeutics
Gavin Oudit (Canada)The ACE/Angiotensin-(1-7( Axis of the Renin-Angiotensin System in Heart Failure.
Thiago Verano Braga (Brazil) – Elucidating Mas/MrgD signaling with phosphoptoteomics

SYMPOSIUM 53 –  Heterogeneity in Respiration: New insights from new approaches

Merryn Tawhai (Chair – New Zealand)
– Of mice and men: innovative modelling to relate lung structure to function.
Susan Hopkins (USA) – Imaging of ventilation, perfusion and gas exchange: new methods of assessing lung function.
Peter Wagner (USA) – New methods for measuring muscle metabolism/perfusion distribution: Insights into muscle O2 availability.
Isaac Cano (Spain) – Significance of heterogeneity in lung and muscle for O2 exchange in health and disease.

SYMPOSIUM 54 – Modulation of physiological states of spinal networks to control posture and locomotion: underlying mechanisms and clinical translations

Yuri Gerasimenko (Chair – Russia) – Sensory-motor regulation of posture and locomotion using non-invasive multisegmental spinal cord electrical stimulation.
Ursula S. Hofstoetter (Austria) –  Spinal cord stimulation: Harnessing the motor capacity of the lumbar circuitry for movement recovery in paralyzed individuals.
Parag Gad (India) – Subliminal and Suprathreshold Sensorimotor Neuromodulation to Facilitate Locomotion
Yuri Ivanenko (Italy) – Spinal locomotor output in humans and its development,
Reggie Edgerton (USA) – Neuromodulatory strategies for recovery of sensorymotor function after spinal cord injury are ready to be the speakers of the Symposium.

SYMPOSIUM 55 – Priming for health: The relevance of the brain-gut communication

Ludmila Filaretova (Russia) – The hypothalamic-pituitary adrenocortical axis as gastroprotective hormonal component of the brain-gut axis
Valentin A. Pavlov (Chair – USA) – The vagus nerve and the inflammatory reflex
Izabela Martina Ramos Ribeiro (Brazil) – Brain-liver axis in the control of glucose production by central action of insulin
Andreas Stengel (Germany) – Alteration of gut-brain signaling under conditions of obesity

SYMPOSIUM 56 – Oxidative stress, aging and neurodegeneration

Thomas Foster (USA) – Age-related changes in redox regulation of NMDA receptors.
Yohei Okubo (Japan) – Nitric oxide contributes to epileptic seizure-induced neuronal death.
Marco T. Nunez (Chile) – Parkinson disease: The mitochondria-iron link.
Roberto De Pasquale (Brazil) – Reactive oxygen species and synaptic plasticity in helth and disease.
Andrea Paula-Lima (Chair – Chile) – Reactive oxygen species mediate synaptic plasticity defects in a model of Alzheimer´s Disease.

SYMPOSIUM 57 – Diaphragm plasticity in ageing & disease: Therapies for muscle weakness go from strength to strength!

Coen Ottenheijm (Netherlands) – Restoration of diaphragm fibre strength in critically ill patients.
Sarah M. Greising (Chair – USA) – Age-related sarcopenia in diaphragm muscle.
Esther Barreiro (Spain) – Diaphragm dysfunction in cancer cachexia: mechanisms and therapies.
Ken O’Halloran (Ireland) – Hypoxia-induced diaphragm dysfunction: Strengthening the case for antioxidant intervention in respiratory patients.

SYMPOSIUM 58 – New Microscopy Techniques in Physiology

Tao Xu (China) – The role of HID-1 in secretory vesicle maturation revealed by three-dimensional electron microscopy.
Jennifer L. Stow – (Chair – Australia) – The role of signaling adaptors in macrophage activation investigated by lattice light sheet microscopy.
Francesca Bottanelli – (USA) – Live-cell stimulated emission depletion (STED) nanoscopy of protein sorting at the Golgi.

SYMPOSIUM 59 – Hypothalamic regulation of the cardiovascular system

Hui-Lin Pan (Chair – USA) – Glutamatergic input to hypothalamic presympathetic neurons in hypertension.
Roger A. Dampney (Australia) – Hypothalamic and midbrain mechanisms regulating coordinated cardiovascular, respiratory and behavioral responses.
Lisete C. Michelini (Brazil) – PVN – a master guide for autonomic control in health and disease.

SYMPOSIUM 60 – Gravitational Physiology, Aging and Medicine

Nandu Goswami (Chair – Austria) – Parrallels between spaceflight and Aging
Andrew P. Blaber (Canada) – Integrative Physiology, Aging and Spaceflight: The Cardio-postural reflex
Kishore K. Deepak (India) – Cardiovascular adjustments during lower body negative pressure induction
Giovanna Valenti (Italy) – Aquaporins and Vasopressin: Current Perspectives in Aging and Spaceflight
Jean-Pierre Montani (Switzerland) – Post-prandial orthostatic hypotension in the elderly: precipitating factors and countermeasures